EZ Cap鈩_Human IL-21 mRNA (m1唯, HA tag)

EZ Cap™ Human IL-21 mRNA (m1Ψ, HA tag)

Author: ApexBio

shortsummary:

Human IL-21 mRNA with Cap 1 structure and HA tag sequence, modified by N1-Methylpseudo-UTP (m1Ψ), providing higher transcription efficiency and suppressing RNA-mediated innate immune activation.

Concanavalin A Solution

DeliveryTime:

In stock

halt protease and phosphatase inhibitor cocktail

ShippingType:

Dry ice

description:

IL-21 is a cytokine secreted by T cells and belongs to the tetraalpha spiral cytokine family. It plays a multifunctional role in the immune system, primarily affecting the function of B cells, T cells, and natural killer cells (NK cells). IL-21 activates the JAK/STAT signaling pathway by binding to its specific receptor IL-21R, thereby regulating the proliferation, differentiation and function of immune cells. In B cells, IL-21 promotes antibody production and B cell maturation. In T cells, it helps regulate the differentiation of Th17 cells and Tfh cells and enhances the function of cytotoxic T cells. In addition, IL-21 can also enhance the cytotoxic effect of NK cells. Because of its importance in immune regulation, IL-21 has potential therapeutic applications in a variety of pathological conditions such as autoimmune diseases, infections, and cancers.

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APExBIO Technology LLC is a premier provider of Small Molecule Inhibitors/Activators, Compound Libraries, Peptides, Assay Kits, Fluorescent Labels, Enzymes, Modified Nucleotides, mRNA synthesis and various tools for Molecular Biology. We carry a broad product line in over 25851 different research areas such as cancer, immunology, neurosciences, apoptosis and epigenetics etc. Based in USA (Houston, Texas), we have been serving the needs of customers across the world.